c-di-AMP (Cyclic diadenylate) is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP (Cyclic diadenylate) is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP (Cyclic diadenylate) acts as a potent mucosal adjuvant stimulating both humoral and cellular responses[1][2][3][4].
Molecular Weight:
658.41
Purity:
99.29
CAS Number:
[54447-84-6]
Formula:
C20H24N10O12P2
Target:
Bacterial,Endogenous Metabolite,STING
Application Notes:
MCE Product type: Reference compound
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