RL648_81 is a specific KQT-like subfamily 2/3 (KCNQ2/3) activator with an EC50 of 190 nM. RL648_81 robustly shifts the V1/2 of KCNQ2/3 channels towards hyperpolarized potentials.RL648_81 does not shift the V1/2 of either KCNQ4 or KCNQ5.RL648_81 has the potential for neurologic disorders associated with neuronal hyperexcitability research[1].
Molecular Weight:
371.33
Purity:
99.49
CAS Number:
[1919050-87-5]
Formula:
C17H17F4N3O2
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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