c-di-AMP diammonium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP diammonium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP diammonium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses[1][2][3][4].
Molecular Weight:
692.47
Purity:
99.36
Formula:
C20H30N12O12P2
Target:
Bacterial,Endogenous Metabolite,STING
Application Notes:
MCE Product type: Reference compound
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