Trk-IN-2 is a pan-Trk kinase inhibitor with a TrkA enzyme IC50 of 9 nM, cell-based IC50 of 7 nM, and oral activity.Trk-IN-2 exhibits pharmacodynamic effects in rat models of inflammatory pain and neuropathic pain.Trk-IN-2 can be used for the research of inflammatory pain, neuropathic pain[1].
Molecular Weight:
468.53
CAS Number:
[1614229-04-7]
Formula:
C24H24N10O
Target:
Trk Receptor
Application Notes:
MCE Product type: Reference compound
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