Denfivontinib (G-749) is a potent, oral active and ATP competitive FLT3 inhibitor, with IC50s of 0.4 nM and 0.6 nM for FLT3 wild type and FLT3-D835Y, respectively. Denfivontinib can be used for the research of agent resistance for acute myeloid leukemia (AML)[1].
Molecular Weight:
521.41
Purity:
98
CAS Number:
[1457983-28-6]
Formula:
C25H25BrN6O2
Target:
Apoptosis,FLT3
Application Notes:
MCE Product type: Reference compound1
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