ZK 216348 ((+)-ZK 216348) is a nonsteroidal selective glucocorticoid receptor agonist with an IC50 of 20.3 nM. ZK 216348 also binds to Progesterone and mineralocorticoid receptors with IC50s of 20.4 nM and 79.9 nM, respectively. ZK 216348 has antiinflammatory activity similar to Prednisolone and induces less transactivation-mediated side effects[1][2].
Molecular Weight:
476.45
Purity:
99.93
CAS Number:
[669073-68-1]
Formula:
C24H23F3N2O5
Target:
Glucocorticoid Receptor
Application Notes:
MCE Product type: Reference compound1
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