AP22161 is a potent and selective Src SH2 domain inhibitor with an IC50 of 0.24 µM. AP22161 exhibits >120-fold selectivity over Yes SH2 (IC50 = 29.38 µM) and ZAP SH2 (IC50 = 421.86 µM). AP22161 inhibits Src-dependent cellular activity and diminishes osteoclast resorptive activity. AP22161 can be used for osteoporosis research[1].
Molecular Weight:
577.67
CAS Number:
[268741-42-0]
Formula:
C32H39N3O7
Target:
Src
Application Notes:
MCE Product type: Reference compound
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