PKUMDL-WQ-2201, CAS [[592474-91-4]]

Product Overview

• Article Name: PKUMDL-WQ-2201, CAS [[592474-91-4]]
• Biozol Catalog Number: MCE-HY-123418
• Supplier Catalog Number: HY-123418
• Alternative Catalog Number: MCE-HY-123418-100MG,MCE-HY-123418-25MG,MCE-HY-123418-50MG,MCE-HY-123418-10MMX1ML,MCE-HY-123418-10MG,MCE-HY-123418-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PKUMDL-WQ-2201 is a PHGDH non-NAD+-competing allosteric inhibitor (IC50=35.7 µM). PKUMDL-WQ-2201 also inhibits PHGDH mutants with IC50s of 69 µM (T59A) and >300 µM (T56AK57A), respectively. PKUMDL-WQ-2201 inhibits de novo serine synthesis in cancer cells, and reduces tumor growth[1][2].

Product Properties

• Molecular Weight: 351.81
• Purity: 98.45
• CAS Number: [592474-91-4]
• Formula: C15H14ClN3O3S
• Target: Phosphoglycerate Dehydrogenase (PHGDH)

Application Notes

• Application Notes: MCE Product type: Reference compound