ML216 (CID-49852229) is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC50s of 2.98 µM and 0.97 µM for BLMfull-length and BLM636-1298, respectively. ML216 inhibits ssDNA-dependent ATPase activity of BLM with a Ki of 1.76 µM. Antitumor avtivity[1][2].
Molecular Weight:
383.32
Purity:
99.89
CAS Number:
[1430213-30-1]
Formula:
C15H9F4N5OS
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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