HJC0416 is a potent and orally active STAT3 inhibitor. HJC0416 shows antiprolifeative activity and induces Apoptosis. HJC0416 decreases the expression of p-STAT3 (Tyr-705), Cyclin D1 and increases the expression of cleaved caspase-3 protein. HJC0416 shows anti-tumor activity[1].
Molecular Weight:
392.86
CAS Number:
[1617518-22-5]
Formula:
C18H17ClN2O4S
Target:
Apoptosis,STAT
Application Notes:
MCE Product type: Reference compound
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