MMV008138 is a species-selective IspD (enzyme 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase)-targeting antimalarial agent, with an IC50 of 44 nM for PfIspD (P. falciparum IspD). MMV008138 inhibits the growth of P. falciparum Dd2 strain with an IC50 of 250 nM[1][2].
Molecular Weight:
361.22
Purity:
98.49
CAS Number:
[1679333-73-3]
Formula:
C18H14Cl2N2O2
Target:
Parasite
Application Notes:
MCE Product type: Reference compound
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