GNE-375 is a potent and highly selective BRD9 inhibitor with an IC50 of 5 nM. GNE-375 shows >100-fold selective for BRD9 over BRD4, TAF1, and CECR2. GNE-375 decreases BRD9 binding to chromatin[1].
Molecular Weight:
451.51
Purity:
99.93
CAS Number:
[1926989-06-1]
Formula:
C25H29N3O5
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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