PD-156707 is an orally active, nonpeptide and selective Endothelin-A receptor antagonist. PD-156707 binds to human ET-A and ET-B receptors with Ki values of 0.17 nM and 133.8 nM, respectively. PD-156707 shows reversal of established chronic hypoxic pulmonary hypertension in rats. PD-156707 can be used for the study of diseases associated with abnormal ET-A receptor activation, particularly pulmonary hypertension, stroke, and heart failure[1][2].
Molecular Weight:
528.48
Purity:
99.92
CAS Number:
[162412-70-6]
Formula:
C28H25NaO9
Target:
Endothelin Receptor
Application Notes:
MCE Product type: Reference compound
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