RWJ-49815 is a histidine kinase inhibitor (IC50 = 1.6 uM). RWJ-49815 inhibits the autophosphorylation of kinase A in the KinA-Spo0F two-component signal transduction system in vitro. RWJ-49815 inhibits the growth of bacteria such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus pneumoniae. RWJ-49815 also inhibits the growth of Fungal such as Saccharomyces cerevisiae and Candida albicans[1][2].
Molecular Weight:
449.59
CAS Number:
[193282-45-0]
Formula:
C30H31N3O
Target:
Bacterial,Fungal
Application Notes:
MCE Product type: Reference compound
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