RUSKI-201 is a potent and specific Hedgehog acyltransferase (Hhat) inhibitor, with an IC50 of 0.20 µM. RUSKI-201 is able to block Hh signaling from Shh overexpressing cells and inhibits Hh palmitoylation. RUSKI-201 is potential Hhat chemical probe in cells and can used in studies of Hhat catalytic function[1].
Molecular Weight:
357.51
CAS Number:
[1458031-48-5]
Formula:
C20H27N3OS
Target:
Hedgehog
Application Notes:
MCE Product type: Reference compound
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