KIN1400 is a potent IRF3 activator. KIN1400 triggers IRF3-dependent innate immune antiviral genes (RIG-I, MDA5, IFIT1, and Mx1) and IFN-beta expression. KIN1400 inhibits WNV and DV, two mosquito-borne members of the Flaviviridae and the genus Flavivirus. KIN1400 also inhibits HCV replication. KIN1400 induces innate antiviral immunity through a MAVS-IRF3 axis[1].
Molecular Weight:
449.47
Purity:
98.1
CAS Number:
[446826-86-4]
Formula:
C24H17F2N3O2S
Target:
HCV,IFNAR
Application Notes:
MCE Product type: Reference compound1
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