KPT-6566 is a selective and covalent prolyl isomerase PIN1 inhibitor, covalently binds to the catalytic site of PIN1, selectively inhibits and degrades PIN1. KPT-6566 shows an IC50 value of 640 nM and a Ki value of 625.2 nM for PIN1 PPIase domain. KPT-6566 can be used for the research of cancer[1].
Molecular Weight:
443.54
Purity:
98
CAS Number:
[881487-77-0]
Formula:
C22H21NO5S2
Target:
PIN1
Application Notes:
MCE Product type: Reference compound
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