MX107 is a selective and potent survivin inhibitor that suppresses triple-negative breast cancer (TNBC) cell proliferation. MX107 induces degradation of survivin and inhibitor-of-apoptosis proteins (IAPs), which inhibits nuclear factor kappaB (NF-kappaB) activation induced by DNA damage. MX107 enhances tumoricidal efficacy of genotoxic treatments synergized with chemotherapeutic drugs[1].
Molecular Weight:
376.49
CAS Number:
[2170102-50-6]
Formula:
C24H28N2O2
Target:
IAP,NF-kappaB,Survivin
Application Notes:
MCE Product type: Reference compound
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