UniPR1331 is an orally active 3beta-hydroxy-delta5-choline acid derivative that inhibits Eph-ephrin interactions. UniPR1331 blocks the interaction of VEGFR2 with its natural ligand vascular endothelial growth factor and inhibits subsequent autophosphorylation, signaling, and pro-angiogenic activation of endothelial cells. UniPR1331 exhibits anti-angiogenesis, anti-cancer and anti-inflammation effects. UniPR1331 can be used for the researches of cancer and inflammation, such as glioma and colitis[1][2][3].
Molecular Weight:
560.77
Purity:
96.41
CAS Number:
[1809170-59-9]
Formula:
C35H48N2O4
Target:
Ephrin Receptor,VEGFR
Application Notes:
Reference compound
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