VU6007477 is a brain-penetrant, selective M1 positive allosteric modulator (PAM) with an EC50 value of 230 nM. VU6007477 is also a human P-glycoprotein (P-gp) substrate with moderate permeability. VU6007477 displays improved central nervous system (CNS) penetration over the hydroxylated congeners. VU6007477 a pyranyl amide derivative, which is promising for research of robust cholinergic seizure activity[1].
Molecular Weight:
430.50
CAS Number:
[2220141-46-6]
Formula:
C24H26N6O2
Target:
P-glycoprotein
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
