SGC-AAK1-1, a chemical probe, is a potent and selective AAK1 (AP2 associated kinase 1) inhibitor with an IC50 of 270 nM and a Ki of 9 nM. SGC-AAK1-1 also potently inhibits BMP2K. SGC-AAK1-1 is used to study Wnt pathway related to AAK1[1].
Molecular Weight:
427.52
Purity:
98.93
CAS Number:
[2247894-32-0]
Formula:
C21H25N5O3S
Target:
AAK1,Wnt
Application Notes:
Reference compound
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