MMRi64 disrupts Mdm2-MdmX interactions. MMRi64 downregulates Mdm2 and MdmX in leukemia cells. MMRi64 induces p53 accumulation, and induces the apoptotic arm of the p53 pathway in leukemia/lymphoma cells. MMRi64 can be used for cancer research[1].
Molecular Weight:
410.30
Purity:
98
CAS Number:
[430458-66-5]
Formula:
C22H17Cl2N3O
Target:
Apoptosis,MDM-2/p53
Application Notes:
Reference compound
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