HG-12-6 is a type II inhibitor of IRAK4. HG-12-6 shows preferential binding to unphosphorylated inactive IRAK4 with an IC50 of 165 nM. HG-12-6 can modulate IRAK4 activity in autoimmunity and inflammation[1].
Molecular Weight:
580.62
CAS Number:
[2222354-57-4]
Formula:
C29H27F3N6O2S
Target:
IRAK
Application Notes:
Reference compound
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