Raphin1 (acetate), CAS [[2242616-04-0]]

Product Overview

• Article Name: Raphin1 (acetate), CAS [[2242616-04-0]]
• Biozol Catalog Number: MCE-HY-123960A
• Supplier Catalog Number: HY-123960A
• Alternative Catalog Number: MCE-HY-123960A-10MG,MCE-HY-123960A-10MMX1ML,MCE-HY-123960A-5MG,MCE-HY-123960A-50MG,MCE-HY-123960A-25MG,MCE-HY-123960A-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Raphin1 acetate is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). Raphin1 acetate binds strongly to the R15B-PP1c holophosphatase (Kd=33 nM), and shows ~30-fold selective in binding R15B-PP1c over R15A-PP1c. Raphin1 acetate crosses the blood-brain barrier, and reduces organismal and molecular deficits in a mouse model of a protein misfolding disease[1].

Product Properties

• Molecular Weight: 291.13
• Purity: 99.93
• CAS Number: [2242616-04-0]
• Formula: C10H12Cl2N4O2
• Target: Phosphatase

Application Notes

• Application Notes: Reference compound