ZK159222, a 25-carboxylic ester analogue of 1alpha,25-(OH)2D3, is a potent 1alpha,25-(OH)2D3 receptor (VDR) antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators. ZK159222 has a partial agonistic character[1].
Molecular Weight:
512.72
Purity:
99.23
CAS Number:
[156965-15-0]
Formula:
C32H48O5
Target:
VD/VDR
Application Notes:
Reference compound
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