ISO-92 in an inhibitor of MIF. ISO-92 selectively inhibits MIF inflammatory activity with an IC50 of 550 nM. ISO-92 inhibits hypoxia-induced proliferation of CCL-210 cell line dose-dependently. ISO-92 significantly reduces the thickness of pulmonary vascular wall in mouse hypoxia models. ISO-92 can be studied in inflammatory and neurological research[1][2].
Molecular Weight:
309.33
CAS Number:
[899433-49-9]
Formula:
C16H20FNO4
Target:
Macrophage migration inhibitory factor (MIF)
Application Notes:
MCE Product type: Reference compound
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