MPT0G211 is a potent, orally active and selective HDAC6 inhibitor (IC50=0.291 nM). MPT0G211 displays >1000-fold selective for HDAC6 over other HDAC isoforms. MPT0G211 can penetrate the blood-brain barrier. MPT0G211 ameliorates tau phosphorylation and cognitive deficits in an Alzheimers disease model. MPT0G211 has anti-metastatic and neuroprotective effects. Anticancer activities[1][2][3].
Molecular Weight:
293.32
Purity:
99.79
CAS Number:
[2151853-97-1]
Formula:
C17H15N3O2
Target:
HDAC
Application Notes:
MCE Product type: Reference compound
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