TEI-9647, a Vitamin D3 Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 inhibits VDR/VDRE-mediated genomic actions of 1alpha,25(OH)2D3. TEI-9647 inhibits bone resorption and HL-60 cell differentiation induced by of 1alpha,25(OH)2D3. TEI-9647 has the potential for suppressing the excessive bone resorption and osteoclast formation in Pagets disease[1][2][3].
Molecular Weight:
426.59
Purity:
99.88
CAS Number:
[173388-20-0]
Formula:
C27H38O4
Target:
VD/VDR
Application Notes:
MCE Product type: Reference compound
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