HS56 is an ATP-competitive dual Pim/DAPK3 inhibitor with Ki values of 0.26, 0.208, 2.94, and >100 µM for DAPK3, Pim-3, Pim-1, and Pim-2, respectively. HS56 inhibits LC20 phosphorylation and smooth muscle contraction. HS56 decreases blood pressure in spontaneously hypertensive mice. HS56 can be used in research of hypertension[1].
Molecular Weight:
317.75
Purity:
99.6
CAS Number:
[922050-57-5]
Formula:
C13H8ClN5OS
Target:
DAPK,Pim
Application Notes:
MCE Product type: Reference compound
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