BAY-8040 is a pyrimidopyridazine derivative which has inhibitory activity against human neutrophil elastase (HNE). BAY-8040 decreases cardiac remodeling and ameliorates cardiac function in a Monocrotaline (HY-N0750)-induced rat model for pulmonary arterial hypertension. BAY-8040 is promising for research of inflammatory pathologies and cardiopulmonary pathologies[1][2].
Molecular Weight:
427.38
CAS Number:
[1194453-23-0]
Formula:
C21H16F3N5O2
Target:
Elastase
Application Notes:
MCE Product type: Reference compound
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