BRD2492 (compound 6d) is a potent, selective HDAC1 and HDAC2 inhibitor with IC50s of 13.2 nM and 77.2 nM, respecrtively. BRD2492 exhibits >100-fold selectivity for HDAC1/2 over selectivity over HDAC3 and HDAC6. BRD2492 inhibits breast cancer cell lines growth with IC50s of 1.01 µM and 11.13 µM for T-47D and MCF-7 cells, respectively[1].
Molecular Weight:
346.38
Purity:
99.18
CAS Number:
[1821669-43-5]
Formula:
C20H18N4O2
Target:
HDAC
Application Notes:
MCE Product type: Reference compound
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