6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C). IC50 value: Target: K-Ras G12C 6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors [2].
Molecular Weight:
476.12
CAS Number:
[1469338-01-9]
Formula:
C20H30ClN3O2S3
Target:
Ras
Application Notes:
MCE Product type: Reference compound
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