6H05 TFA is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C). IC50 value: Target: K-Ras G12C 6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors [2].
Molecular Weight:
590.14
Purity:
99.02
CAS Number:
[2061344-88-3]
Formula:
C22H31ClF3N3O4S3
Target:
Ras
Application Notes:
MCE Product type: Reference compound1
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