IT-901 is an orally active and potent NF-kappaB subunit c-Rel inhibitor with an IC50 of 0.1 µM, 3 µM for NF-kappaB DNA binding and c-Rel DNA binding, respectively. IT-901, a bioactive naphthalenethiobarbiturate derivative, has the potential for human lymphoid tumors and ameliorate graft-versus-host disease (GVHD)[1][2].
Molecular Weight:
342.37
Purity:
99.32
CAS Number:
[1584121-99-2]
Formula:
C17H14N2O4S
Target:
NF-kappaB
Application Notes:
Reference compound
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