Voruciclib is an orally active and selective CDK inhibitor with Ki values of 0.626 nM-9.1 nM. Voruciclib potently blocks CDK9, the transcriptional regulator of MCL-1. Voruciclib represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL)[1].
Molecular Weight:
469.84
Purity:
99.77
CAS Number:
[1000023-04-0]
Formula:
C22H19ClF3NO5
Target:
CDK
Application Notes:
Reference compound
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