Voruciclib hydrochloride is an orally active and selective CDK inhibitor with Ki values of 0.626 nM-9.1 nM. Voruciclib hydrochloride potently blocks CDK9, the transcriptional regulator of MCL-1. Voruciclib hydrochloride represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL)[1].
Molecular Weight:
506.30
Purity:
99.23
CAS Number:
[1000023-05-1]
Formula:
C22H20Cl2F3NO5
Target:
CDK
Application Notes:
Reference compound
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