Zgwatinib (SOMG-833) is a potent, selective, and ATP-competitive c-MET inhibitor, with an IC50 of 0.93 nM against c-MET, over 10,000-fold more potent compared with 19 tyrosine kinases (including c-MET family members and highly homologous kinases). Zgwatinib potently inhibits c-MET-driven cell proliferation. Zgwatinib as a potential candidate agent for c-MET-driven human cancers research[1].
Molecular Weight:
445.44
CAS Number:
[1268264-10-3]
Formula:
C22H22F3N5O2
Target:
c-Met/HGFR
Application Notes:
Reference compound
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