ADM 12 is a highly selective transient receptor potential ankyrin 1 (TRPA1) channel antagonist. ADM 12 blocks nitroglycerin (NTG)-induced trigeminal hyperalgesia in animal models, reducing expression of pain-related genes (c-Fos, TRPA1) and neuropeptides (CGRP, SP). ADM_12 is promising for research of migraine and neuropathic pain[1].
Molecular Weight:
327.48
CAS Number:
[1644134-60-0]
Formula:
C11H21NO4S3
Target:
TRP Channel
Application Notes:
MCE Product type: Reference compound1
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