LEI-106 is a potent, dual sn-1-Diacylglycerol lipase alpha (DAGL-alpha)/ABHD6 inhibitor with an IC50 of 18 nM for DAGL-alpha and a Ki of 0.8 µM for ABHD6. LEI-106 inhibits the hydrolysis of [14C]-sn-1-oleoyl-2-arachidonoyl-glycerol, the natural substrate of DAGL-alpha, with a Ki of 0.7 µM[1].
Molecular Weight:
481.56
Purity:
99.9
CAS Number:
[1620582-23-1]
Formula:
C26H27NO6S
Target:
DAGL,MAGL
Application Notes:
MCE Product type: Reference compound
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