T-3364366 is a reversible, slow-binding, thienopyrimidinone delta-5 desaturase (D5D) inhibitor with IC50s of 1.9 nM and 2.1 nM in HepG2 and RLN-10 cells, respectively. T-3364366 exhibits potent D5D (IC500=19 nM) inhibitory activity and excellent selectivity away from delta-6 desaturase (D6D, IC50=6200 nM) and delta-9 desaturase (stearoyl-CoA desaturase, SCD,50 >10000 nM) in the enzymatic activity assay[1].
Molecular Weight:
443.46
Purity:
99.80
CAS Number:
[1356354-09-0]
Formula:
C18H16F3N3O3S2
Target:
Stearoyl-CoA Desaturase (SCD)
Application Notes:
MCE Product type: Reference compound
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