RO6889678 is a highly potent HBV capsid formation inhibitor with a complex absorption, distribution, metabolism, and excretion (ADME) profile. RO6889678 is a potent inducer of CYP3A4 and coregulated proteins in human hepatocytes. RO6889678 is metabolized by a combination of CYP3A4-mediated oxidation and UDP-glucuronosyltransferase UGT1A3- and UGT1A1-mediated direct glucuronidation[1].
Molecular Weight:
494.92
CAS Number:
[1578153-27-1]
Formula:
C21H20ClFN4O5S
Target:
Cytochrome P450,HBV
Application Notes:
MCE Product type: Reference compound
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