Asnuciclib (CDKI-73, LS-007) is an orally active and highly efficacious CDK9 inhibitor, with Ki values of 4 nM, 4 nM and 3 nM for CDK9, CDK1 and CDK2, respectively. Asnuciclib down-regulates the RNAPII phosphorylation. Asnuciclib is also a novel pharmacological inhibitor of Rab11 cargo delivery and innate immune secretion[1][2][3][4].
Molecular Weight:
394.45
Purity:
99.76
CAS Number:
[1421693-22-2]
Formula:
C15H15FN6O2S2
Target:
Apoptosis,CDK
Application Notes:
MCE Product type: Reference compound
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