Unguinol is a depsidone originally isolated from A. unguis. It is an inhibitor of pyruvate phosphate dikinase (PPDK, IC50=42.3 µM). It inhibits the growth of plants utilizing C4, but not C3, carbon fixation. Unguinol also inhibits the growth of the bacteria S. aureus and V. harveyi (GI50s=8.7 and 69.5 µM, respectively) and H460, MCF-7, and SF-268 cancer cells (GI50s=28.2, 50.8, and 44.3 µM, respectively).
Molecular Weight:
326.34
CAS Number:
[36587-59-4]
Formula:
C19H18O5
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound
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