Difludiazepam (Ro 07-4065), a benzodiazepine derivative, is a GABAA receptor ligand with an IC50 of 4.1 nM. Difludiazepam binds to an allosteric site on the GABAA receptor to potentiate the receptors response to GABA, reducing neuron excitability. Difludiazepam contains halogenated groups at the ortho position of its phenyl ring[1][2].
Molecular Weight:
320.72
Purity:
98.9
CAS Number:
[39080-67-6]
Formula:
C16H11ClF2N2O
Target:
GABA Receptor
Application Notes:
MCE Product type: Reference compound
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