Oleocanthal is an orally active phenolic seciridoid compound. Oleocanthal can be extracted from olive oil. Oleocanthal inhibits COX-1 and COX-2, reduces ROS and NO, and upregulates Nrf-2 and HO-1. Oleocanthal reduces Abeta deposition. Oleocanthal exhibits anti-Leishmania activity against promastigotes and amastigotes of L. major, with IC50 values of 18.7 and 87 µg/mL, respectively. Oleocanthal exhibits anticancer activity against colon, breast, liver, and melanoma cancers. Oleocanthal also exhibits anti-inflammatory and neuroprotective properties. Oleocanthal can be used in Alzheimers disease research[1][2][3][4][5][6].
Molecular Weight:
304.34
Purity:
99
CAS Number:
[289030-99-5]
Formula:
C17H20O5
Target:
Amyloid-beta,COX,Heme Oxygenase (HO),Keap1-Nrf2,NO Synthase,Parasite,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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