JI130 (JI051 derivative ) is a stabilizer for the Hes1-PHB2 interaction. JI130 inhibits the ability of Hes1 to repress transcription. JI130 significantly reduces the tumor growth in a murine pancreatic tumor model and has the potential for managing pancreatic cancer[1].
Molecular Weight:
376.45
Purity:
99.41
CAS Number:
[2234271-86-2]
Formula:
C23H24N2O3
Target:
Notch
Application Notes:
MCE Product type: Reference compound
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