Duocarmycin SA, CAS [[130288-24-3]]

Product Overview

• Article Name: Duocarmycin SA, CAS [[130288-24-3]]
• Biozol Catalog Number: MCE-HY-12456
• Supplier Catalog Number: HY-12456
• Alternative Catalog Number: MCE-HY-12456-1MG,MCE-HY-12456-5MG,MCE-HY-12456-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Duocarmycin SA is an orally active antitumor antibiotic with an IC50 of 10 pM[1]. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro[2].

Product Properties

• Molecular Weight: 477.47
• Purity: 99.89
• CAS Number: [130288-24-3]
• Formula: C25H23N3O7
• Target: ADC Payload,Antibiotic,Apoptosis,DNA Alkylator/Crosslinker,Necroptosis

Application Notes

• Application Notes: MCE Product type: ADC Related