JG-231 is an allosteric inhibitor of heat shock protein 70 (Hsp70). JG - 231 inhibits the binding of Hsp70 and BAG family proteins, including inhibition of Hsp70 and BAG1 with a Ki of 0.11 µM. JG-231 inhibits proliferation of tumor cells and induces apoptosis. JG-231 has antitumor activity[1][2].
Molecular Weight:
619.47
Purity:
98.47
CAS Number:
[1627126-59-3]
Formula:
C22H18BrCl2N3OS4
Target:
Apoptosis,HSP
Application Notes:
MCE Product type: Reference compound
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