AMXT-1501 tetrahydrochloride is an orally active polyamine transport inhibitor. AMXT1501 blocks tumor growth in immunocompetent mice but not in athymic nude mice lacking T cells[1]. Combination of DFMO and AMXT-1501 induces caspase-3 mediated apoptosis in NB cell lines[2].
Molecular Weight:
714.77
Purity:
98
CAS Number:
[2444815-84-1]
Formula:
C32H72Cl4N6O2
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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