GPI-1046 is an orally active, antibiotic-free immunophilin ligand that reduces ethanol intake by upregulating glutamate transporter 1 (GLT1) in the prefrontal cortex (PFC) and nucleus accumbens core (NAc-core). GPI-1046 improves human immunodeficiency virus (HIV)-associated sensory neuropathy (HIV-SN) by attenuating store-operated calcium (SOC) entry. GPI-1046 has neuroprotective activity[1][2][3].
Molecular Weight:
360.45
Purity:
99.79
CAS Number:
[186452-09-5]
Formula:
C20H28N2O4
Target:
EAAT,HIV
Application Notes:
MCE Product type: Reference compound
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